بررسی اثرات تجویز کلسیم در سندرم پیش از قاعدگی

Premenstrural syndrome(PMS) which includes psychological and physical symptoms regularly occurs during the second half of the menstrual cycle and it is estimated to affect up to 95% of women to some degree. Five percent of these women will be affected so severely that this causes disruption in their daily activities and social interactions. The main cause of this syndrome is unknown and a lot of women suffer from PMS therefore, the treatment is very important. Recently, it has been found that calcium supplementation is useful for curing symptoms of PMS. The object of the present study was to find the effect of calcium on reducing the symptoms of premenstrual syndrome. First, medical and paramedical female students were screened for 20 symptoms of cyclically premenstrual symptoms through administering a questionnaire. Later, 100 women were selected for this trial. Symptoms were prospectively documented over 3 menstrual cycles with a daily rating scale that had 20 symptoms of PMS. Participants received 1000 mg of effervescent calcium per day in 5 days, when the symptoms were maximum in the previous cycles. Daily documentation of symptoms were monitored. After 3 months data analysis was done. Among 20 symptoms of PMS, 12 symptoms including psychological symptoms such as fatigue, sleep disorders, irritability, depression, appetite changing, and physical symptoms such as body dismorphia, breast tenderness, acnea, headache, arthralgia, low back pain, weight increase had significant reduction or they completely disappeared with calcium supplementation. Using 1000 mg calcium supplementation per day in the second half of menstrual cycle for 5 days in women affected with premenstrual syndrome results in overall 62% reduction of psychologial symptoms and 61% reduction of physical symptoms. Thus, more study in this field can be recommended to find out daily consumption of 1000 mg calcium supplementation by women who suffer from premenstrual syndrome will significantly reduce overall symptoms and prevent disruption of daily activities and social interaction.